原著論文

Akiko Tanaka, Takanobu Takata, Hidemasa Katsumi, Yasuhisa Sawai, Hiroyuki Nakano, Chika Yoneto, Kunio Yoneto, Tomoyuki Furubayashi, Toshiyasu Sakane. Development of Freeze-Dried Hyaluronic Acid Sheets for Healing Oral Mucositis: Influence of Hyaluronic Acid Molecular Weight and Nicotinamide Mononucleotide Loading on Healing Efficacy. J Funct Biomater. 10;17(3):137 (2026).

Masaki Morishita, Mizuho Atari, Kisa Masuda, Kazuya Higashiwaki, Chikae Sakata, Tomonori Waku, Hidemasa Katsumi, Akira Yamamoto. Optimizing Prebiotic Saccharides in Culture Medium for the Bifidobacteria-Derived Extracellular Vesicles as Biomaterial Immunoadjuvant. Biol Pharm Bull. 48(7):986-993 (2025).

Yuki Matsushima, Reo Kainuma, Hidemasa Katsumi, Akiko Tanaka, Tomoyuki Furubayashi, Toshiyasu Sakane. Tablet Color Changes Due to Light Irradiation and Titanium Dioxide: Color Change Prevention Using Plasticizers. AAPS PharmSciTech. 26(5):142 (2025).

Yusuke Hatakawa, Akiko Tanaka, Tomoyuki Furubayashi, Hidemasa Katsumi, Rina Nakamura, Motomi Konishi, Toshifumi Akizawa, Toshiyasu Sakane. Efficient nose-to-brain delivery of nine residues peptide (JAL-TA9) exhibiting hydrolytic activity against amyloid-β. Eur J Pharm Biopharm. 208:114661 (2025).

Masaki Morishita, Mizuho Makabe, Chisa Shinohara, Ami Fukumori, Shiori Morita, Yuki Terada, Syunsuke Miyai, Hidemasa Katsumi, Akira Yamamoto. Versatile functionalization of Bifidobacteria-derived extracellular vesicles using amino acid metabolic labeling and click chemistry for immunotherapy. Int. J. Pharm., 661, 124410 (2024) .

Akiko Tanaka, Akiko Kiriyama, Ayaka Sano, Cho Changung, Hidemasa Katsumi, Akira Yamamoto, Tomoyuki Furubayashi. Left-Right Difference in Brain Pharmacokinetics Following Nasal Administration Via One-Site Nostrils. J. Pharm. Sci., 113, 2633-2640 (2024).

Shugo Yamashita, Azusa Imanishi, Suzuna Ueki, Serina Okamoto, Shunsuke Kimura, Akiko Kiriyama. Pharmacokinetic-Pharmacodynamic Analysis of pH-Responsive Doxorubicin-Releasing Micelles with Anticancer Activity. Mol Pharm.21(7):3173-3185 (2024).

Shugo Yamashita, Shunsuke Kimura, Akiko Kiriyama. Tumoral Pharmacokinetic-Pharmacodynamic Simulation of Doxorubicin-Encapsulated Polymeric Micelles Using a Tissue-Isolated Tumor Perfusion System. Mol Pharm. 21(11):5736-5748 (2024).

Akiko Kiriyama, Shunsuke Kimura, Shugo Yamashita. Exploring the multiple effects of nifedipine and captopril administration in spontaneously hypertensive rats through pharmacokinetic-pharmacodynamic analyses. Pharmacol Res Perspect. 12(4):e1249 (2024).

Shugo Yamashita, Karen Azuma, Yuka Tanaka, Shunsuke Kimura, Akiko Kiriyama. Variations in the inner core affect the pharmacokinetics of indomethacin-encapsulated polymeric micelles. Int J Pharm. 654:123933 (2024).

Masaki Morishita, Masakatsu Kida, Tomomi Motomura, Rihito Tsukamoto, Mizuho Atari, Kazuya Higashiwaki, Kisa Masuda, Hidemasa Katsumi, Akira Yamamoto. Elucidation of the Tissue Distribution and Host Immunostimulatory Activity of Exogenously Administered Probiotic-Derived Extracellular Vesicles for Immunoadjuvant. Mol. Pharm., 20, 6104-6113 (2023).

Masaki Morishita, Ryoga Nagata, Kento Maruoka, Ayaka Higuchi, Shota Sasaki, Sorari Wada, Hidemasa Katsumi, Akira Yamamoto. Lymphatic Transport and Immune Activation Effect by Locally Administered Extracellular Vesicles from Saccharomyces cerevisiae as Biocompatible Vaccine Adjuvants. Biol. Pharm. Bull., 46, 1427-1434 (2023).

Kei Suzuki-Mishima, Akiko Tanaka, Nahoko Kato-Kogoe, Koji Yamanegi, Azumi Hirata, Kunio Yoneto, Chika Yoneto, Wataru Hamada, Hidemasa Katsumi, Tomoyuki Furubayashi, Hiroyuki Nakano, Toshiyasu Sakane and Takaaki Ueno. Topical Administration of Freeze-Dried Sheets of Hyaluronic Acid Promotes the Healing of Oral Mucositis in a Hamster Model. Journal of Hard Tissue Biology, 32, 223–230 (2023).

Ayaka Higuchi, Masaki Morishita, Ryoga Nagata, Kento Maruoka, Hidemasa Katsumi, Akira Yamamoto. Functional characterization of extracellular vesicles from baker’s yeast Saccharomyces cerevisiae as a novel vaccine material for immune cell maturation. J. Pharm. Sci., 112, 525-534 (2023).

Akiko Kiriyama, Shunsuke Kimura, Shugo Yamashita. Pharmacokinetic/Pharmacodynamic Models of an Alzheimer's Drug, Donepezil, in Rats. Drug Metab Dispos. 51(3):329-337 (2023).

Hidemasa Katsumi, Sho Kitada, Shintaro Yasuoka, Rie Takashima, Tomoki Imanishi, Rina Tanaka, Satoru Matsuura, Hiroyuki Kimura, Hidekazu Kawashima, Masaki Morishita, Akira Yamamoto. L-serine-modified poly-L-lysine as a biodegradable kidney-targeted drug carrier for the efficient radionuclide therapy of renal cell carcinoma. Pharmaceutics, 14, 1946 (2022).

Kohei Ogawa, Hidemasa Katsumi, Daiki Nomura, Yasushi Moroto, Morishita Morishita, Akira Yamamoto. A Dense layer of polyethyleneglycol and zwitterionic bone targeting peptide on the surface of stereocomplex polylactide-polyethyleneglycol nanoparticles improves shelf-storage stability and the serum compatibility. J. Pharm. Sci., 111, 2888-2897 (2022).

Shugo Yamashita, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Phosphorylated serine-modified polyamidoamine dendrimer as an osteoid surface-targeting drug carrier. Mol. Pharm., 19, 2573-2582 (2022).

Kohei Ogawa, Hidemasa Katsumi, Yasushi Moroto, Masaki Morishita, Akira Yamamoto. Processing Parameters and ion excipients affect the physicochemical characteristics of the stereocomplex-formed polylactide-b-polyethylene glycol nanoparticles and their pharmacokinetics. Pharmaceutics, 14, 568 (2022).

Masaki Morishita, Risa Sagayama, Yuta Yamawaki, Marina Yamaguchi, Hidemasa Katsumi, Akira Yamamoto. Activation of host immune cells by probiotic-derived extracellular vesicles via TLR2-mediated signaling pathways. Biol. Pharm. Bull., 45, 354-359 (2022).

Mariko Kimoto, Toshiyasu Sakane, Hidemasa Katsumi, Akira Yamamoto. Simultaneous Determination of active pharmaceutical ingredients and water-soluble polymers: analysis of dissolution profiles from sustained-release formulations and mechanisms involved. Chem. Pharm. Bull., 70, 138-145 (2022).

Mariko Kimoto, Toshiyasu Sakane, Hidemasa Katsumi, Akira Yamamoto. Quick and simultaneous Analysis of dissolved active pharmaceutical ingredients and formulation excipients from the dissolution test utilizing UHPLC and charged aerosol detector. AAPS PharmSciTech., 22, 262 (2021).

Kohei Ogawa, Hidemasa Katsumi, Kazuyuki Takata, Daiki Nomura, Yasushi Moroto, Hideyuki Kitamura, Chise Takaki, Masaki Morishita, Akira Yamamoto. Orthogonal characterization and pharmacokinetic studies of polylactide-polyethyleneglycol polymeric nanoparticles with different physicochemical properties. Int. J. Pharm., 608, 121120 (2021).

Masaki Morishita, Maho Horita, Ayaka Higuchi, Maho Marui, Hidemasa Katsumi, Akira Yamamoto. Characterizing different probiotic-derived extracellular vesicles as a novel adjuvant for immunotherapy. Mol. Pharm., 18, 1080-1092 (2021).

Chihiro Naito, Tomoko Yamaguchi, Hidemasa Katsumi, Suyo Kimura, Sachi Kamei, Masaki Morishita, Kenji Kawabata, Akira Yamamoto. Human induced pluripotent stem cell-based skin for assessing transdermal drug permeability and irritancy. Biol. Pharm. Bull., 44, 140-143 (2021).

Yukiya Takayama, Kosuke Kusamori, Chihiro Tsukimori, Yosuke Shimizu, Mika Hayashi, Ikumi Kiyama, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto, Makiya Nishikawa. Anticancer drug-loaded mesenchymal stem cells for targeted cancer therapy. J. Control. Release, 329, 1090-1101 (2021).

Hiroki Ukai, Ayako Imanishi, Ayaka Kaneda, Erika Kimura, Miku Koyama, Masaki Morishita, Hidemasa Katsumi, Akira Yamamoto. Absorption-enhancing mechanisms of Capryol 90, a novel absorption enhancer, for improving the intestinal absorption of poorly absorbed drugs: Contributions to trans- or para-cellular pathways. Pharm. Res., 37, 248 (2020).

Shugo Yamashita, Hidemasa Katsumi, Erika Shimizu, Yuto Nakao, Ayane Yoshioka, Minako Fukui, Hiroyuki Kimura, Toshiyasu Sakane, Akira Yamamoto. Dendrimer-based micelles with highly potent targeting to sites of active bone turnover for the treatment of bone metastasis. Eur. J. Pharm. Biopharm., 157, 85-96 (2020).

Hiroki Ukai, Kazuki Iwasa, Takamasa Deguchi, Masaki Morishita, Hidemasa Katsumi, Akira Yamamoto. Enhanced intestinal absorption of insulin by capryol 90, a novel absorption enhancer in rats: Implications in oral insulin delivery. Pharmaceutics, 12, 462 (2020).

Tomoyuki Furubayashi, Daisuke Inoue, Noriko Nishiyama, Akiko Tanaka, Reiko Yutani, Shunsuke Kimura, Hidemasa Katsumi, Akira Yamamoto, Toshiyasu Sakane. Comparison of various cell lines and three-dimensional mucociliary tissue model systems to estimate drug permeability using an in vitro transport study to predict nasal drug absorption in rats. Pharmaceutics, 12, 79 (2020).

Hiroki Ukai, Arisa Kawagoe, Erika Sato, Masaki Morishita, Hidemasa Katsumi, Akira Yamamoto. Propylene glycol caprylate as a novel potential absorption enhancer for improving the intestinal absorption of insulin: Efficacy, safety, and absorption-enhancing mechanisms. J. Pharm. Sci., 109, 1483-1492 (2020).

Akiko Tanaka, Kentaro Takayama, Tomoyuki Furubayashi, Kenji Mori, Yuki Takemura, Mayumi Amano, Chiaki Maeda, Daisuke Inoue, Shunsuke Kimura, Akiko Kiriyama, Hidemasa Katsumi, Mikiya Miyazato, Kenji Kangawa, Toshiyasu Sakane, Yoshio Hayashi, Akira Yamamoto. Transnasal delivery of the peptide agonist specific to neuromedin-U receptor 2 to the brain for the treatment of obesity. Mol. Pharm., 17, 32-39 (2020).

Hidemasa Katsumi, Rie Takashima, Hiroe Suzuki, Natsuko Hirai, Satoru Matsuura, Hiroyuki Kimura, Masaki Morishita, Akira Yamamoto. S-nitrosylated l-serine-modified dendrimer as a kidney-targeting nitric oxide donor for prevention of renal ischaemia/reperfusion injury. Free Radic. Res., 54, 841-847 (2020).

Mari Tsujimura, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto, Makiya Nishikawa. Cell-based interferon gene therapy using proliferation-controllable, interferon-releasing mesenchymal stem cells. Sci. Rep., 9, 18869 (2019).

Chihiro Naito, Hidemasa Katsumi, Kunio Yoneto, Mao Omura, Mayuko Nishidono, Sachi Kamei, Akiya Mizoguchi, Ayaka Tamba, Akiko Tanaka, Masaki Morishita, Akira Yamamoto. Development of a phosphoric acid-mediated hyaluronic acid gel sheet for efficient transdermal delivery of alendronate for anti-osteoporotic therapy. Pharmaceutics, 11, 643 (2019).

Chihiro Naito, Tomoko Yamaguchi, Hidemasa Katsumi, Suyo Kimura, Sachi Kamei, Masaki Morishita, Toshiyasu Sakane, Kenji Kawabata, Akira Yamamoto. Utility of three-dimensional skin from human-induced pluripotent stem cells as a tool to evaluate transdermal drug permeation. J. Pharm. Sci., 108, 3524-3527 (2019).

Tammam Alama, Kousuke Kusamori, Masaki Morishita, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Mechanistic studies on the absorption-enhancing effects of gemini surfactant on the intestinal absorption of poorly absorbed hydrophilic drugs in rats. Pharmaceutics, 11, 170 (2019).

Kosuke Sakai, Hidemasa Katsumi, Kentaro Kamano, Kiyo Yamauchi, Ayuko Hajima, Masaki Morishita, Toshiyasu Sakane, Akira Yamamoto. Hepatic and intrahepatic targeting of hydrogen sulfide prodrug by bioconjugation. Biol. Pharm. Bull., 42, 273-279 (2019).

Kasirawat Sawangrat, Shugo Yamashita, Akiko Tanaka, Masaki Morishita, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Modulation of intestinal transport and absorption of topotecan, a BCRP substrate, by various pharmaceutical excipients and their inhibitory mechanisms of BCRP transporter. J. Pharm. Sci., 108, 1315-1325 (2019).

Shunsuke Kimura, Akiko Kiriyama, Kaeko Araki, Mai Yoshizumi, Masakazu Enomura, Daisuke Inoue, Tomoyuki Furubayashi, Reiko Yutani, Reiko Teraoka, Akiko Tanaka, Kosuke Kusamori, Hidemasa Katsumi, Akira Yamamoto, Katsumi Iga. Novel strategy for improving the bioavailability of curcumin based on a new membrane transport mechanism that directly involves solid particles. Eur. J. Pharm. Biopharm., 122, 1-5 (2018).

Satoru Matsuura, Hidemasa Katsumi, Hiroe Suzuki, Natsuko Hirai, Rie Takashima, Masaki Morishita, Toshiyasu Sakane, Akira Yamamoto. l-Cysteine and l-serine modified dendrimer with multiple reduced thiols as a kidney-targeting reactive oxygen species scavenger to prevent renal ischemia/reperfusion injury. Pharmaceutics, 10, 251 (2018).

Shugo Yamashita, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Bone-targeting dendrimer for the delivery of methotrexate and treatment of bone metastasis. J. Drug Target., 26, 818-828 (2018).

Chihiro Naito, Hidemasa Katsumi, Tomoko Suzuki, Ying-shu Quan, Fumio Kamiyama, Toshiyasu Sakane, Akira Yamamoto. Self-dissolving microneedle arrays for transdermal absorption enhancement of human parathyroid hormone (1-34). Pharmaceutics, 10, 215 (2018).

Satoru Matsuura, Hidemasa Katsumi, Hiroe Suzuki, Natsuko Hirai, Hidetaka Hayashi, Kazuhiro Koshino, Takahiro Higuchi, Yusuke Yagi, Hiroyuki Kimura, Toshiyasu Sakane, Akira Yamamoto. l-Serine–modified polyamidoamine dendrimer as a highly potent renal targeting drug carrier. Proc. Natl. Acad. Sci. U. S. A., 115, 10511-10516 (2018).

Daisuke Inoue, Shunsuke Kimura, Akiko Kiriyama, Hidemasa Katsumi, Akira Yamamoto, Ken-ichi Ogawara, Kazutaka Higaki, Akiko Tanaka, Reiko Yutani, Toshiyasu Sakane, Tomoyuki Furubayashi. Quantitative estimation of the effect of nasal mucociliary function on in vivo absorption of norfloxacin after intranasal administration to rats. Mol. Pharm., 15, 4462-4469 (2018).

Kosuke Sakai, Hidemasa Katsumi, Mayu Sugiura, Ayaka Tamba, Kentaro Kamano, Kiyo Yamauchi, Yosui Tamura, Toshiyasu Sakane, Akira Yamamoto. Pharmacokinetics and preventive effects of sulfo-albumin as a novel macromolecular hydrogen sulfide prodrug on carbon tetrachloride-induced hepatic injury. J. Pharm. Sci., 107, 2686-2693 (2018).

Kasirawat Sawangrat, Masaki Morishita, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Effects of various pharmaceutical excipients on the intestinal transport and absorption of sulfasalazine, a typical substrate of breast cancer resistance protein transporter. J. Pharm. Sci., 107, 2946-2956 (2018).

Mari Tsujimura, Kosuke Kusamori, Chihiro Oda, Airi Miyazaki, Hidemasa Katsumi, Toshiyasu Sakane, Makiya Nishikawa, Akira Yamamoto. Regulation of proliferation and functioning of transplanted cells by using herpes simplex virus thymidine kinase gene in mice. J. Control. Release, 275, 78-84 (2018).

Daisuke Inoue, Akiko Tanaka, Shunsuke Kimura, Akiko Kiriyama, Hidemasa Katsumi, Akira Yamamoto, Ken-ichi Ogawara, Toshikiro Kimura, Kazutaka Higaki, Reiko Yutani, Toshiyasu Sakane, Tomoyuki Furubayashi. The relationship between in vivo nasal drug clearance and in vitro nasal mucociliary clearance: Application to the prediction of nasal drug absorption. Eur. J. Pharm. Sci., 117, 21-26 (2018).

Akiko Tanaka, Tomoyuki Furubayashi, Mari Arai, Daisuke Inoue, Shunsuke Kimura, Akiko Kiriyama, Kosuke Kusamori, Hidemasa Katsumi, Reiko Yutani, Toshiyasu Sakane, Akira Yamamoto. Delivery of oxytocin to the brain for the treatment of autism spectrum disorder by nasal application. Mol. Pharm., 15, 1105-1111 (2018).

Xinpeng Li, Sachiyo Uehara, Kasirawat Sawangrat, Masaki Morishita, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Improvement of intestinal absorption of curcumin by cyclodextrins and the mechanisms underlying absorption enhancement. Int. J. Pharm., 535, 340-349 (2018).

Shugo Yamashita, Hidemasa Katsumi, Nozomi Hibino, Yugo Isobe, Yumiko Yagi, Yuka Tanaka, Saki Yamada, Chihiro Naito, Akira Yamamoto. Development of PEGylated aspartic acid-modified liposome as a bone-targeting carrier for the delivery of paclitaxel and treatment of bone metastasis. Biomaterials, 154, 74-85 (2018).

Shunsuke Kimura, Akiko Kiriyama, Erika Nishimura, Shiori Sakata, Daisuke Inoue, Tomoyuki Furubayashi, Reiko Yutani, Akiko Tanaka, Kosuke Kusamori, Hidemasa Katsumi, Katsumi Iga, Akira Yamamoto, Toshiyasu Sakane. Novel strategy for the systemic delivery of furosemide based on a new drug transport mechanism. Biol. Pharm. Bull., 41, 1769-1777 (2018).

Yukiya Takayama, Kosuke Kusamori, Mika Hayashi, Noriko Tanabe, Satoru Matsuura, Mari Tsujimura, Hidemasa Katsumi, Toshiyasu Sakane, Makiya Nishikawa, Akira Yamamoto. Long-term drug modification to the surface of mesenchymal stem cells by the avidin-biotin complex method. Sci. Rep., 7, 16953 (2017).

Xinpeng Li, Ami Kawamura, Yusuke Sato, Masaki Morishita, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Improvement of the solubility and intestinal absorption of curcumin by N-acyl taurates and elucidation of the absorption-enhancing mechanisms. Biol. Pharm. Bull., 40, 2175-2182 (2017).
Hidemasa Katsumi, Yutaro Tanaka, Kaori Hitomi, Shu Liu, Ying Shu Quan, Fumio Kamiyama, Toshiyasu Sakane, Akira Yamamoto. Efficient transdermal delivery of alendronate, a nitrogen-containing bisphosphonate, using tip-loaded self-dissolving microneedle arrays for the treatment of osteoporosis. Pharmaceutics, 9, 29 (2017).

Shugo Yamashita, Hidemasa Katsumi, Nozomi Hibino, Yugo Isobe, Yumiko Yagi, Kosuke Kusamori, Toshiyasu Sakane, Akira Yamamoto. Development of PEGylated carboxylic acid-modified polyamidoamine dendrimers as bone-targeting carriers for the treatment of bone diseases. J. Control. Release, 262, 10-17 (2017).

Akiko Tanaka, Tomoyuki Furubayashi, Yuki Enomura, Tomoki Hori, Rina Shimomura, Chiaki Maeda, Shunsuke Kimura, Daisuke Inoue, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Nasal drug absorption from powder formulations: effect of fluid volume changes on the mucosal surface. Biol. Pharm. Bull., 40, 212-219 (2017).

Akiko Tanaka, Tomoyuki Furubayashi, Hitomi Yamasaki, Katsuko Takano, Mayuko Kawakami, Shunsuke Kimura, Daisuke Inoue, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. The enhancement of nasal drug absorption from powder formulations by the addition of sodium carboxymethyl cellulose. IEEE Transactions on NanoBioscience, 15, 798-803 (2016).

Tammam Alama, Hiroko Katayama, Sachiko Hirai, Shizuka Ono, Ayumi Kajiyama, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Enhanced oral delivery of alendronate by sucrose fatty acids esters in rats and their absorption-enhancing mechanisms. Int. J. Pharm., 515, 476-489 (2016).

Wanting Zhao, Alama Tammam, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Effects of two polyoxyethylene alkyl ethers on the function of intestinal P-glycoprotein and their inhibitory mechanisms. J. Pharm. Sci., 105, 3668-3679 (2016).

Yuka Nakaya, Alama Tammam, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Enhanced oral delivery of bisphosphonate by novel absorption enhancers: improvement of intestinal absorption of alendronate by N-Acyl Amino Acids and N-Acyl Taurates and Their Absorption-Enhancing Mechanisms. J. Pharm. Sci., 105, 3680-3690 (2016).

Akiko Tanaka, Tomoyuki Furubayashi, Akihiko Matsushita, Daisuke Inoue, Shunsuke Kimura, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Nasal absorption of macromolecules from powder formulations and effects of sodium carboxymethyl cellulose on their absorption. PLoS One, 11, e0159150 (2016).

Masashi Adachi, Yuta Hinatsu, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Manabu Nakatani, Koichi Wada and Akira Yamamoto. Effects of manufacturing methods on dissolution and absorption of ketoconazole in the presence of organic acid as a pH modifier. AAPS PharmSciTech., 18, 1203-1212 (2016).

Hidemasa Katsumi, Makiya Nishikawa, Rikiya Hirosaki, Tatsuya Okuda, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida, Toshiyasu Sakane, Akira Yamamoto. Development of PEGylated cysteine-modified lysine dendrimers with multiple reduced thiols to prevent hepatic ischemia/reperfusion injury. Mol. Pharm., 13, 2867-2873 (2016).

Wanting Zhao, Sachiyo Uehera, Keiichiro Tanaka, Shuhei Tadokoro, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Effects of polyoxyethylene alkyl ethers on the intestinal transport and absorption of rhodamine 123: A P-glycoprotein substrate by in vitro and in vivo studies. J. Pharm. Sci., 105, 1526-1534 (2016).

Dan Wu, Hidemasa Katsumi, Ying-shu Quan, Fumio Kamiyama, Kosuke Kusamori, Toshiyasu Sakane, Akira Yamamoto. Permeation of sumatriptan succinate across human skin using multiple types of self-dissolving microneedle arrays fabricated from sodium hyaluronate. J. Drug Target., 24, 752-758 (2016).

Kosuke Kusamori, Hidemasa Katsumi, Ryota Sakai, Rie Hayashi, Yuka Hirai, Yutaro Tanaka, Kaori Hitomi, Ying-shu Quan, Fumio Kamiyama, Keigo Yamada, Shun-ichiro Sumida, Kazumasa Kishi, Katsunori Hashiba, Toshiyasu Sakane, Akira Yamamoto. Development of a drug-coated microneedle array and its application for transdermal delivery of interferon alpha. Biofabrication, 8, 015006 (2016).

Tammam Alama, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Absorption-enhancing effects of gemini surfactant on the intestinal absorption of poorly absorbed hydrophilic drugs including peptide and protein drugs in rats. Int. J. Pharm., 499, 58-66 (2016).

Shunsuke Kimura, Sachiha Kasatani, Megumi Tanaka, Kaeko Araki, Masakazu Enomura, Kei Moriyama, Daisuke Inoue, Tomoyuki Furubayashi, Akiko Tanaka, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Importance of the direct contact of amorphous solid particles with the surface of monolayers for the transepithelial permeation of curcumin. Mol. Pharm., 13, 493-499 (2016).

Shu Liu, Dan Wu, Ying-shu Quan, Fumio Kamiyama, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Improvement of transdermal delivery of exendin-4 using novel tip-loaded microneedle arrays fabricated from hyaluronic acid. Mol. Pharm., 13, 272-279 (2016).

Hidemasa Katsumi, Takunori Mozume, Shin-ichiro Yanagi, Tomohiro Hasei, Tetsushi Watanabe, Toshiyasu Sakane, Akira Yamamoto. Pharmacokinetic and therapeutic efficacy of intrapulmonary administration of zoledronate for the prevention of bone destruction in rheumatoid arthritis. J. Drug Target., 24, 530-536 (2016).

Akiko Tanaka, Tomoyuki Furubayashi, Manami Tomisaki, Mayuko Kawakami, Shunsuke Kimura, Daisuke Inoue, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Nasal drug absorption from powder formulations: The effect of three types of hydroxypropyl cellulose (HPC). Eur. J. Pharm. Sci., 96, 284-289 (2016).

著書

創薬の不可能を可能にする 中分子ペプチド医薬
勝見英正 (担当:分担執筆, 範囲:第3章-2）生理活性ペプチドのDDS)
羊土社 2025年1月

中分子ペプチド医薬で新たな標的を狙う!!
勝見英正, 森下将輝, 山本 昌 (担当:分担執筆, 範囲:第7章 生理活性ペプチドのドラッグデリバリーシステムの開発)
羊土社 2023年

次世代マイクロニードルの開発と応用
勝見英正, 権 英淑, 神山文男, 山本 昌 (担当:分担執筆, 範囲:第2章 ヒアルロン酸マイクロニードルを用いた骨粗鬆症治療薬テリパラチド (hPTH1-34)の経皮デリバリー)
シーエムシー出版 2022年12月

中分子創薬に向けたDDS開発の新展開
山本昌, 鵜飼裕紀, 森下将輝, 勝見英正 (担当:分担執筆, 範囲:新規吸収促進剤Capryol90によるペプチド?タンパク性医薬品の消化管吸収性改善ならびにその吸収促進機構の解析)
シーエムシー出版 2022年3月

医薬品におけるDDS技術開発と製剤への応用
山本 昌, 勝見英正, 森下将輝 (担当:分担執筆, 範囲:第1章 第1 節 医薬品の経口投与における薬物吸収改善の方法)
情報機構 2021年

次世代吸入製剤とデバイスの開発
勝見英正, 山本 昌 (担当:分担執筆, 範囲:関節リウマチの骨破壊抑制を目指したビスホスホネートの経肺投与型DDSの開発)
シーエムシー出版 2018年

Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds
Hidemasa Katsumi, Akira Yamamoto (担当:分担執筆, 範囲:Development of transdermal delivery system of peptide and protein drugs using self-dissolving microneedle arrays fabricated from hyaluronic acid.)
Springer 2018年

製剤学（改訂第7版）
勝見英正 (担当:分担執筆, 範囲:第7章 ドラッグデリバリーシステム C. 薬物放出の制御 D. 薬物標的指向の制御)
南江堂 2017年

製剤?包装の改良?工夫点と病院から選ばれる医薬品開発
(担当:分担執筆, 範囲:第4章 剤型?投与経路開発による病院から選ばれる医薬品開発 第9節 マイクロニードルを用いた薬剤投与法開発)
技術情報協会 2017年

製剤学?物理薬剤学
勝見英正 (担当:分担執筆, 範囲:第12章 吸入剤、第13章 ドラッグデリバリーシステム (DDS))
廣川書店 2017年

リンの辞典
勝見英正, 山本 昌 (担当:分担執筆, 範囲:医薬?化成品分野 ビスホスホネート)
朝倉書店 2017年

DDS先端技術
勝見英正, 山本 昌 (担当:分担執筆, 範囲:骨をターゲットとしたDDS)
技術情報協会 2017年

マイクロニードルの製造と応用展開
勝見英正, 山本 昌 (担当:分担執筆, 範囲:ヒアルロン酸を素材とする溶解型マイクロニードルを利用した糖尿病治療薬の経皮デリバリー)
シーエムシー出版 2016年

経皮吸収型製剤開発における基礎と実務への応用
勝見英正, 山本 昌 (担当:分担執筆, 範囲:溶解型ヒアルロン酸マイクロニードルを用いた次世代型経皮吸収型製剤の開発)
技術情報協会 2015年

注射薬?経口製剤に代わる新しい薬剤投与デバイスの開発
勝見英正, 山本 昌 (担当:分担執筆, 範囲:マイクロニードルと製剤開発 [1] 溶解型マイクロニードルを用いた難吸収性薬物の経皮吸収改善)
技術情報協会 2014年

次世代ペプチド医薬創製
勝見英正, 山本 昌 (担当:分担執筆, 範囲:マイクロニードルを用いたペプチド?タンパク性医薬品の次世代型経皮吸収製剤の開発)
メディカルドゥ 2014年

敗血症の診断/治療の実状と戦略 病態?メカニズムをふまえた開発戦略
勝見英正, 山本 昌 (担当:分担執筆, 範囲:製剤学的アプローチによる敗血症治療の研究開発～抗酸化剤のDDS開発と敗血症治療への応用～)
技術情報協会 2013年

応用が拡がるDDS～人体環境から農業?家電まで～
勝見英正, 山本 昌 (担当:分担執筆, 範囲:ヒアルロン酸マイクロニードルを用いたペプチド?タンパク性医薬品の経皮吸収製剤の開発.)
NTS 2013年

非経口投与製剤の開発と応用―次世代型医薬品の新規投与形態の開拓を目指して―
(担当:分担執筆, 範囲:勝見英正、山本 昌: 第13章1 骨粗鬆症治療薬ビスホスホネートの次世代型経皮吸収製剤の開発―新規親水性パッチ及びマイクロニードルを用いた経皮吸収システムの開発―. 勝見英正、山本 昌: 第10章1 骨粗鬆症治療薬ビスホスホネートの経肺投与型DDSの開発.)
シーエムシー出版 2013年

難吸収性薬物の吸収性改善と新規投与製剤の開発
(担当:分担執筆, 範囲:勝見英正、山本 昌: 第5章4 各種製剤添加物を用いたペプチド?タンパク性医薬品の経肺吸収性の改善. 権 英淑、神山文男、勝見英正、山本 昌: 第5章8 マイクロニードルを用いる難吸収性薬物の経皮吸収改善.)
シーエムシー出版 2012年